Episode 5

Published on:

16th Jun 2021

How We Are Making 100 The New 30 - Overview on Longevity Circle

In this installment of How We Are Making 100 The New 30, Dr. Gladden explores the important factors contained within the Longevity Circle.

Ultimately, people are truly invested in their performance when it comes to their physical or athletic experiences. But what they don't understand, is that performance can be linked to an array of different variables. Listen as Dr. Gladden showcases what those variables are and how his team at Gladden Longevity are measuring them to optimize longevity as a whole.

So sit back, relax, and enjoy another insightful conversation surrounding the key elements that comprise the Longevity Circle.


0:20 - People are truly interested in performance

1:45 - Optimizing a growth mindset

4:05 - Optimizing spiritual health is also very important

6:45 - Genetic liabilities and optimizing genetic stability

9:30 - Epigenetic age and the rate of aging

12:00 - Proteostasis and why it's important to clear it out

17:00 - Optimizing our senescent cells and their status

20:30 - Killing of certain senescent cells

23:40 - Focus on Circadian Rhythm and it's importance overall

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Show artwork for How We Are Making 100 The New 30

About the Podcast

How We Are Making 100 The New 30
Rethink your concepts of aging and decline
"How We Are Making 100 The New 30" brings board-certified interventional cardiologist and founder of Apex Health, Human Performance & Longevity Optimization, Dr. Jeffrey Gladden, directly to your doorstep to help you optimize your health and overall longevity.

During his mid-fifties, things took a turn for the worse for Dr. Gladden, personally and professionally. Despite eating what he thought was a healthy diet and exercising regularly, he became very fatigued, to the point that he could hardly get out of bed. Stress and anxiety led to bouts of depression. He was getting burned out on traditional medicine, as it became more and more scripted, focused on compliance, and less about exploring creative and resourceful means of caring for patients. Much of his time and energy was spent fighting insurance companies for coverage for his patients instead of engaging with them for care. Politics between hospitals and competing doctors become cutthroat. At the time, Dr. Gladden had also worked in a catheterization lab for a long time and felt he had “received more than enough radiation for one lifetime.”

Though practicing interventional cardiology had been his calling and livelihood for the last quarter century, Dr. Gladden knew he needed a change for the sake of his own health and that of his family. He threw himself into learning everything he could about functional medicine, bio-identical hormone replacement and age management medicine. This led to diagnosing his own subclinical hypothyroidism. He also did a deep dive into which foods worked best for his body based on genetic, neutragenomic, food sensitivity, gut biome and gut integrity data, becoming more selective in the quality and sources of his food. By eating properly and replacing hormone levels, he began to feel more youthful again.

Now it's time to share his knowledge and experience with you! Sit back, relax, as Dr. Gladden helps you look inward at your own health and shares enlightening conversations surrounding human longevity.